diff --git a/src/octoprint/server/api/slicing.py b/src/octoprint/server/api/slicing.py
index 824faf02..3427bb3b 100644
--- a/src/octoprint/server/api/slicing.py
+++ b/src/octoprint/server/api/slicing.py
@@ -43,6 +43,8 @@ def _etag(configured, lm=None):
 	else:
 		hash.update(repr(sorted(slicingManager.registered_slicers)))
 
+	hash.update("v2") # increment version if we change the API format
+
 	return hash.hexdigest()
 
 
diff --git a/src/octoprint/static/js/app/viewmodels/slicing.js b/src/octoprint/static/js/app/viewmodels/slicing.js
index ae98bed7..d2d47098 100644
--- a/src/octoprint/static/js/app/viewmodels/slicing.js
+++ b/src/octoprint/static/js/app/viewmodels/slicing.js
@@ -4,6 +4,7 @@ $(function() {
 
         self.loginState = parameters[0];
         self.printerProfiles = parameters[1];
+        self.printerState = parameters[2];
 
         self.file = ko.observable(undefined);
         self.target = undefined;
@@ -23,6 +24,8 @@ $(function() {
         self.profiles = ko.observableArray();
         self.printerProfile = ko.observable();
 
+        self.slicerSameDevice = ko.observable();
+
         self.allViewModels = undefined;
 
         self.slicersForFile = function(file) {
@@ -73,6 +76,19 @@ $(function() {
             self.profile(undefined);
         };
 
+        self.metadataForSlicer = function(key) {
+            if (key == undefined || !self.data.hasOwnProperty(key)) {
+                return;
+            }
+
+            var slicer = self.data[key];
+            self.slicerSameDevice(slicer.sameDevice);
+        };
+
+        self.resetMetadata = function() {
+            self.slicerSameDevice(true);
+        };
+
         self.configuredSlicers = ko.pureComputed(function() {
             return _.filter(self.slicers(), function(slicer) {
                 return slicer.configured;
@@ -136,8 +152,10 @@ $(function() {
         self.slicer.subscribe(function(newValue) {
             if (newValue === undefined) {
                 self.resetProfiles();
+                self.resetMetadata();
             } else {
                 self.profilesForSlicer(newValue);
+                self.metadataForSlicer(newValue);
             }
         });
 
@@ -153,7 +171,20 @@ $(function() {
             return self.destinationFilename() != undefined
                 && self.destinationFilename().trim() != ""
                 && self.slicer() != undefined
-                && self.profile() != undefined;
+                && self.profile() != undefined
+                && (!(self.printerState.isPrinting() || self.printerState.isPaused()) || !self.slicerSameDevice());
+        });
+
+        self.sliceButtonTooltip = ko.pureComputed(function() {
+            if (!self.enableSliceButton()) {
+                if ((self.printerState.isPrinting() || self.printerState.isPaused()) && self.slicerSameDevice()) {
+                    return gettext("Cannot slice on the same device while printing");
+                } else {
+                    return gettext("Cannot slice, not all parameters specified");
+                }
+            } else {
+                return gettext("Start the slicing process");
+            }
         });
 
         self.requestData = function() {
@@ -218,6 +249,10 @@ $(function() {
         };
 
         self.slice = function() {
+            if (!self.enableSliceButton()) {
+                return;
+            }
+
             var destinationFilename = self._sanitize(self.destinationFilename());
 
             var destinationExtensions = self.data[self.slicer()] && self.data[self.slicer()].extensions && self.data[self.slicer()].extensions.destination
@@ -275,7 +310,7 @@ $(function() {
 
     OCTOPRINT_VIEWMODELS.push([
         SlicingViewModel,
-        ["loginStateViewModel", "printerProfilesViewModel"],
+        ["loginStateViewModel", "printerProfilesViewModel", "printerStateViewModel"],
         "#slicing_configuration_dialog"
     ]);
 });
diff --git a/src/octoprint/templates/dialogs/slicing.jinja2 b/src/octoprint/templates/dialogs/slicing.jinja2
index 51021027..2d1f9ec6 100644
--- a/src/octoprint/templates/dialogs/slicing.jinja2
+++ b/src/octoprint/templates/dialogs/slicing.jinja2
@@ -16,6 +16,13 @@
                         <select data-bind="options: matchingSlicers, optionsText: 'name', optionsValue: 'key', optionsCaption: '{{ _('Select a slicer...') }}', value: slicer, valueAllowUnset: true"></select>
                     </div>
                 </div>
+                <div class="control-group">
+                    <label class="control-label">{{ _('Runs locally') }}</label>
+                    <div class="controls">
+                        <strong data-bind="text: slicerSameDevice() ? gettext('Yes') : gettext('No')"></strong>
+                        <span class="help-block"><small>{{ _('For performance reasons locally run slicers are disabled while printing') }}</small></span>
+                    </div>
+                </div>
                 <div class="control-group">
                     <label class="control-label">{{ _('Slicing Profile') }}</label>
                     <div class="controls">
@@ -48,6 +55,6 @@
     </div>
     <div class="modal-footer">
         <a href="#" class="btn" data-dismiss="modal" aria-hidden="true">{{ _('Cancel') }}</a>
-        <a href="#" class="btn btn-primary" data-bind="click: function() { if ($root.enableSliceButton()) { $root.slice() } }, enabled: enableSliceButton, css: {disabled: !$root.enableSliceButton()}">{{ _('Slice') }}</a>
+        <a href="#" class="btn btn-primary" data-bind="click: function() { if ($root.enableSliceButton()) { $root.slice() } }, enabled: enableSliceButton, css: {disabled: !$root.enableSliceButton()}, attr: {title: $root.sliceButtonTooltip}">{{ _('Slice') }}</a>
     </div>
 </div>