diff --git a/cara/apps/templates/base/userguide.html.j2 b/cara/apps/templates/base/userguide.html.j2
index 74e6452d..e94e7514 100644
--- a/cara/apps/templates/base/userguide.html.j2
+++ b/cara/apps/templates/base/userguide.html.j2
@@ -70,8 +70,10 @@ The choices are:
SARS-CoV-2 (nominal strain), covering typical strains and variants which are not of concern from an epidemiologic point of view of the virus;
SARS-CoV-2 (Alpha VOC), first identified in the UK at the end of 2020 which is found to be approximately 1.5x more transmissible compared to the non-VOCs;
+
SARS-CoV-2 (Beta VOC), first identified in South Africa in May 2020 which is found to be approximately 1.25x more transmissible compared to the non-VOCs;
SARS-CoV-2 (Gamma VOC), first identified in Brazil in January 2021 which is found to be approximately 2.2x more transmissible compared to the non-VOCs.
SARS-CoV-2 (Delta VOC), first identified in India towards the end of 2020 which is found to be approximately 60% more transmissible compared to the ALPHA VOC.
+
SARS-CoV-2 (Omicron VOC), first identified in South Africa in November 2021 which is found to be at least 2.53x more transmissible compared to the DELTA VOC.
The user can modify the selected variant from the default, according to the prevalence of the different variants in the local area. Access to this information can be found here:
diff --git a/cara/models.py b/cara/models.py
index 012e453e..bbf4557e 100644
--- a/cara/models.py
+++ b/cara/models.py
@@ -481,6 +481,10 @@ Virus.types = {
viral_load_in_sputum=1e9,
infectious_dose=30/1.6,
),
+ 'SARS_CoV_2_B11529': SARSCoV2(
+ viral_load_in_sputum=1e9,
+ infectious_dose=50/4.9841,
+ ),
}
diff --git a/cara/monte_carlo/data.py b/cara/monte_carlo/data.py
index 4415efbb..330d21ab 100644
--- a/cara/monte_carlo/data.py
+++ b/cara/monte_carlo/data.py
@@ -40,6 +40,8 @@ symptomatic_vl_frequencies = LogCustomKernel(
# From CERN-OPEN-2021-04 and refererences therein
+# NB the infectious dose is inversely proportional to infectiousness of the strain
+# i.e. an infectious dose of 80 is 25% more infectious than a dose of 100, (1/(80/100))
virus_distributions = {
'SARS_CoV_2': mc.SARSCoV2(
viral_load_in_sputum=symptomatic_vl_frequencies,
@@ -49,6 +51,10 @@ virus_distributions = {
viral_load_in_sputum=symptomatic_vl_frequencies,
infectious_dose=60,
),
+ 'SARS_CoV_2_B1351': mc.SARSCoV2(
+ viral_load_in_sputum=symptomatic_vl_frequencies,
+ infectious_dose=80,
+ ),
'SARS_CoV_2_P1': mc.SARSCoV2(
viral_load_in_sputum=symptomatic_vl_frequencies,
infectious_dose=100/2.25,
@@ -56,7 +62,11 @@ virus_distributions = {
'SARS_CoV_2_B16172': mc.SARSCoV2(
viral_load_in_sputum=symptomatic_vl_frequencies,
infectious_dose=60/1.6,
- ),
+ ),
+ 'SARS_CoV_2_B11529': mc.SARSCoV2(
+ viral_load_in_sputum=symptomatic_vl_frequencies,
+ infectious_dose=(1/4.9841)*100,
+ ),
}