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Added note on P.1 transmission/Manaus antibody levels.

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James Devine 2021-03-09 11:06:53 +00:00 committed by Nicolas Mounet
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cara/apps/calculator/README.md
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@ -39,12 +39,17 @@ This has a significant effect on the probability of infection.
The choices are:
* `SARS-CoV-2 (nominal strain)`, covering typical strains and varaints which are not of concern from an epidemiologic point of view of the virus;
* `SARS-CoV-2 (B.1.1.7)`, the VOC first identified in the UK at the end of 2020 which is found to be approximately 1.5x more transmissible compared to the non-VOCs;
* `SARS-CoV-2 (P.1)`, the VOC first identified in Brazil in January 2021 which is found to be approximately 2.25x more transmissible compared to the non-VOCs.
* `SARS-CoV-2 (P.1)`, the VOC first identified in Brazil in January 2021 which is found to be approximately 2.2x more transmissible compared to the non-VOCs.
The user can base their choice according to the prevalence of the different variants in the local area. Access to this information can be found here:
* Geneva: https://www.covid19.admin.ch/fr/epidemiologic/virus-variants?detGeo=GE
* Ain (France): https://www.santepubliquefrance.fr/dossiers/coronavirus-covid-19/covid-19-cartographie-des-variants-en-france-donnees-par-region-et-par-departement
N.B. The transmission data for the P.1 variant has been taken from a study data gathered in Manaus, Brazil where the variant was first observed.
The local population in Manaus had very high levels of Covid-19 antibodies (>67%) in recent months.
This factor has been taken into account by the authors of the study, via statistical adjustments to the transmission value (i.e. it has been increased, to account for spread in a population with significant acquired Covid-19 immunity).
However, this value may be revised in the future as more studies of P.1 transmission in different geographical locations become available.
### Room Data
Please enter either the room volume (in m³) or both the floor area (m²) and the room height (m).